C5
适用: 人
WB, IA
宿主: 小鼠
Monoclonal
568
unconjugated
应用备注
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.50-1.500
限制
仅限研究用
状态
Liquid
缓冲液
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
储存液
Thimerosal (Merthiolate)
注意事项
Biohazard Informations: This product contains thimerosal which is hazardous.
储存条件
4 °C/-20 °C
储存方法
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
抗原
C5
(Complement Component 5 (C5))
背景
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes.This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge.An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase.The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections.Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis.[provided by RefSeq]