Dynactin 1 抗体 (AA 1216-1278)
Quick Overview for Dynactin 1 抗体 (AA 1216-1278) (ABIN1885985)
抗原
See all Dynactin 1 (DCTN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1216-1278
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 1216 and 1278 of dynactin 1
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anti-Dynactin 1 (DCTN1) (C-Term) antibody
Verified DCTN1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (C-Term) antibodyDCTN1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (AA 1084-1278) antibodyDCTN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (C-Term) antibodyDCTN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (AA 945-1139) antibodyDCTN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (N-Term) antibodyDCTN1 适用: 人 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Dynactin 1 (DCTN1) (AA 1216-1278) antibodyDCTN1 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) antibodyDCTN1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (AA 1-198) antibodyDCTN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E4-1C2 unconjugated
anti-Dynactin 1 (DCTN1) (C-Term) antibodyDCTN1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Dynactin 1 (DCTN1)
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别名
- dynactin 1
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背景
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This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD.Dynactin binds to both microtubules and cytoplasmic dynein.Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis.This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus.Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).[provided by RefSeq]
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分子量
- 142 kDa
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基因ID
- 1639
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NCBI登录号
- NP_004073, NM_004082
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途径
- M Phase, ER-Nucleus Signaling
抗原
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