RASGRP4 抗体 (AA 108-170)
Quick Overview for RASGRP4 抗体 (AA 108-170) (ABIN1885956)
抗原
See all RASGRP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 108-170
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 108 and 170 of Human RASGRP4
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anti-RAS Guanyl Releasing Protein 4 (RASGRP4) (AA 574-673) antibody
RASGRP4 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-RAS Guanyl Releasing Protein 4 (RASGRP4) (N-Term) antibodyRASGRP4 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 4 (RASGRP4) (AA 1-673) antibodyRASGRP4 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 4 (RASGRP4) (AA 149-198) antibodyRASGRP4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 4 (RASGRP4) (N-Term) antibodyRASGRP4 适用: 人, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- RASGRP4 (RAS Guanyl Releasing Protein 4 (RASGRP4))
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别名
- RASGRP4
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背景
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The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors.It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands.This protein was shown to activate H-Ras in a cation-dependent manner in vitro.Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways.Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development.Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
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分子量
- 75 kDa
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基因ID
- 115727
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NCBI登录号
- NM_170604, NP_733749
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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