DNASE1 抗体 (AA 1-252)
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北京 101111
Quick Overview for DNASE1 抗体 (AA 1-252) (ABIN1885847)
抗原
See all DNASE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-252
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 252 of DNase I
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- DNASE1 (Deoxyribonuclease I (DNASE1))
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别名
- DNase I
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背景
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This gene encodes a member of the DNase family.This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner.At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record.Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease.A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity.Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.[provided by RefSeq]
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分子量
- 31 kDa
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基因ID
- 1773
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NCBI登录号
- NM_005223, NP_005214
抗原
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