HUS1 抗体 (AA 1-243)
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北京 101111
Quick Overview for HUS1 抗体 (AA 1-243) (ABIN1885832)
抗原
See all HUS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-243
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 243 of HUS1
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
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别名
- HUS1
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背景
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The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage.This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1.In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin.The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event.[provided by RefSeq]
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分子量
- 32 kDa
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基因ID
- 3364
抗原
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