Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.500
限制
仅限研究用
状态
Liquid
缓冲液
0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
储存液
Thimerosal (Merthiolate)
注意事项
Biohazard Informations: This product contains thimerosal which is hazardous.
储存条件
4 °C/-20 °C
储存方法
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
抗原
HUS1
(HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
别名
HUS1
背景
The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage.This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1.In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin.The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event.[provided by RefSeq]