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PFKM 抗体 (AA 1-223)

PFKM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1885803
发货至: 中国
  • 抗原 See all PFKM 抗体
    PFKM (phosphofructokinase, Muscle (PFKM))
    抗原表位
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-223
    适用
    • 66
    • 28
    • 23
    • 14
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 59
    • 8
    • 8
    • 7
    克隆类型
    • 67
    • 15
    多克隆
    标记
    • 46
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PFKM antibody is un-conjugated
    应用范围
    • 63
    • 36
    • 29
    • 14
    • 12
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 223 of Human PFKM
    Top Product
    Discover our top product PFKM Primary Antibody
  • 应用备注
    Suggested dilutions:
    Western blotting: 1.500-1.3000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    Biohazard Informations: This product contains thimerosal which is hazardous.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    PFKM (phosphofructokinase, Muscle (PFKM))
    别名
    PFK-1 (PFKM 产品)
    别名
    GSD7 antibody, PFK-1 antibody, PFK1 antibody, PFKA antibody, PFKX antibody, AI131669 antibody, PFK-A antibody, PFK-M antibody, Pfk-4 antibody, Pfk4 antibody, Pfka antibody, Pfkx antibody, Pfk-M antibody, M-PFK antibody, PFKM antibody, pfkm antibody, zgc:92344 antibody, pfk antibody, im:7137110 antibody, wu:fc58g11 antibody, phosphofructokinase, muscle antibody, phosphofructokinase, platelet antibody, phosphofructokinase, muscle a antibody, phosphofructokinase, muscle S homeolog antibody, phosphofructokinase, muscle b antibody, PFKM antibody, Pfkm antibody, PFKP antibody, pfkma antibody, pfkm.S antibody, pfkmb antibody
    背景
    The PFKM gene encodes the muscle isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11).PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis.Mammalian PFK is a tetramer made up of various combinations of 3 subunits: muscle (PFKM), liver (PFKL, MIM 171860), and platelet (PFKP, MIM 171840), the genes for which are located on chromosomes 12q13, 21q22, and 10p, respectively.The composition of the tetramers differs according to the tissue type.Muscle and liver PFK are a homotetramers of 4M and 4L subunits, respectively.Erythrocytes contain both L and M subunits, which randomly tetramerize to form M4, L4, and M3L, M2L2, and ML3 hybrid forms of the holoenzyme (Vora et al., 1980 [PubMed 6444721], Raben and Sherman, 1995 [PubMed 7550225]).[supplied by OMIM]
    分子量
    85 kDa
    基因ID
    5213
    NCBI登录号
    NM_000289, NP_000280
    途径
    Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effect
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