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PFKM 抗体 (AA 1-223)

This anti-PFKM antibody is a 兔 多克隆 antibody detecting PFKM in WB. Suitable for 人.
产品编号 ABIN1885803
发货至: 中国

Quick Overview for PFKM 抗体 (AA 1-223) (ABIN1885803)

抗原

See all PFKM 抗体
PFKM (phosphofructokinase, Muscle (PFKM))

适用

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宿主

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克隆类型

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多克隆

标记

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This PFKM antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-223

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 223 of Human PFKM
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    PFKM (phosphofructokinase, Muscle (PFKM))

    别名

    PFK-1

    背景

    The PFKM gene encodes the muscle isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11).PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis.Mammalian PFK is a tetramer made up of various combinations of 3 subunits: muscle (PFKM), liver (PFKL, MIM 171860), and platelet (PFKP, MIM 171840), the genes for which are located on chromosomes 12q13, 21q22, and 10p, respectively.The composition of the tetramers differs according to the tissue type.Muscle and liver PFK are a homotetramers of 4M and 4L subunits, respectively.Erythrocytes contain both L and M subunits, which randomly tetramerize to form M4, L4, and M3L, M2L2, and ML3 hybrid forms of the holoenzyme (Vora et al., 1980 [PubMed 6444721], Raben and Sherman, 1995 [PubMed 7550225]).[supplied by OMIM]

    分子量

    85 kDa

    基因ID

    5213

    NCBI登录号

    NM_000289, NP_000280

    途径

    Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effect
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