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FKBP4 抗体 (AA 1-177)

This anti-FKBP4 antibody is a 兔 多克隆 antibody detecting FKBP4 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN1885705
发货至: 中国

Quick Overview for FKBP4 抗体 (AA 1-177) (ABIN1885705)

抗原

See all FKBP4 抗体
FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

适用

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  • 1

宿主

  • 68
  • 28
  • 2

克隆类型

  • 62
  • 36
多克隆

标记

  • 52
  • 6
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This FKBP4 antibody is un-conjugated

应用范围

  • 80
  • 45
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  • 17
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  • 6
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-177

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 177 of FKBP52
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.500
    Immunofluorescence: 1.100-1.200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

    别名

    FKBP52

    背景

    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking.This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506.It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase.It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors.This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines.Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy.The human genome contains several non-transcribed pseudogenes similar to this gene.[provided by RefSeq]

    分子量

    52 kDa

    基因ID

    2288

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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