GSTa2 抗体 (AA 1-166)
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北京 101111
Quick Overview for GSTa2 抗体 (AA 1-166) (ABIN1885674)
抗原
See all GSTa2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-166
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 166 of Human GSTA2
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
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别名
- glutathione S-transferase alpha 2
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背景
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Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.The genes encoding these enzymes are known to be highly polymorphic.These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs.At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-tranferase belonging to the alpha class.The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver.In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.[provided by RefSeq]
Synonyms: GST2, GTA2, GTH2, GSTA2-2, MGC10525 -
分子量
- 26 kDa
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基因ID
- 2939
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NCBI登录号
- NP_000837, NM_000846
抗原
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