DUSP8 抗体 (AA 1-14)
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Quick Overview for DUSP8 抗体 (AA 1-14) (ABIN1885611)
抗原
See all DUSP8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-14
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 14 of Human DUSP8
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))
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别名
- DUSP8
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背景
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The protein encoded by this gene is a member of the dualprotein phosphatase subfamily.These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation.Different members of the family of dualphosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.[provided by RefSeq]
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分子量
- 66 kDa
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基因ID
- 1850
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NCBI登录号
- NP_004411, NM_004420
抗原
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