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Cofilin 2 抗体 (AA 1-127)

This anti-Cofilin 2 antibody is a 兔 多克隆 antibody detecting Cofilin 2 in WB 和 IF. Suitable for 人.
产品编号 ABIN1885597
发货至: 中国

Quick Overview for Cofilin 2 抗体 (AA 1-127) (ABIN1885597)

抗原

See all Cofilin 2 (CFL2) 抗体
Cofilin 2 (CFL2)

适用

  • 49
  • 23
  • 9
  • 5
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 1

宿主

  • 46
  • 2
  • 1

克隆类型

  • 47
  • 2
多克隆

标记

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  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
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  • 1
  • 1
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This Cofilin 2 antibody is un-conjugated

应用范围

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  • 15
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  • 2
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  • 1
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 10
    • 9
    • 7
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    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-127

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 127 of Cofilin 2
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunofluorescence: 1.100-1.200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    Cofilin 2 (CFL2)

    别名

    Cofilin 2

    背景

    Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.(Gillett et al., 1996 [PubMed 8800436]).Cofilin-2 is a member of the AC group of proteins that also includes cofilin-1 (CFL1) and destrin (DSTN, MIM 609114), all of which regulate actin-filament dynamics (Bamburg et al., 1999 [PubMed 10461190], Maciver and Hussey, 2002).The CFL2 gene encodes a skeletal muscle-specific isoform (Vartiainen et al., 2002 [PubMed 11809832]) localized to the thin filaments, where it exerts its effect on actin, in part through interactions with tropomyosins (Ono and Ono, 2002 [PubMed 11901171]).[supplied by OMIM]

    分子量

    19 kDa

    基因ID

    1073

    途径

    Caspase Cascade in Apoptosis
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