DC-SIGN/CD209 抗体 (Extracellular Domain)
Quick Overview for DC-SIGN/CD209 抗体 (Extracellular Domain) (ABIN1885521)
抗原
See all DC-SIGN/CD209 (CD209) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Extracellular Domain
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纯化方法
- Immunoaffinity chromotography purified IgG
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免疫原
- Raised against a recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN (1).
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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储存条件
- -20 °C
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储存方法
- Can be stored at -20 °C, stable for one year.
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有效期
- 12 months
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- DC-SIGN/CD209 (CD209) (CD209)
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别名
- DC-SIGN
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背景
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Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes , where DCs hand over HIV to CD4+ T lymphocytes.DCs also amplify the amount of virus and extend the duration of viral infectivity.Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN.ICAM-3 is the natural ligand for DC-SIGN.A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently.DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR (8).The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.
Synonyms: DC-SIGN (5D7), Dendritic cell-specific ICAM-3-grabbing nonintegrin 1 -
UniProt
- Q9NNX6
抗原
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