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USP14 抗体

This anti-USP14 antibody is a 小鼠 单克隆 antibody detecting USP14 in WB. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1882288
发货至: 中国

Quick Overview for USP14 抗体 (ABIN1882288)

抗原

See all USP14 抗体
USP14 (Ubiquitin Specific Peptidase 14 (USP14))

适用

  • 62
  • 9
  • 7
  • 5
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 51
  • 10
小鼠

克隆类型

  • 44
  • 18
单克隆

标记

  • 34
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This USP14 antibody is un-conjugated

应用范围

  • 44
  • 26
  • 15
  • 9
  • 7
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

889CT6-2-1
  • 纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    Purified His-tagged USP14 protein was used to produced this monoclonal antibody.

    亚型

    IgG1
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Carrascal, Ovelleiro, Casas, Gay, Abian: "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment." in: Journal of proteome research, Vol. 7, Issue 12, pp. 5167-76, (2009) (PubMed).

    Koulich, Li, DeMartino: "Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome." in: Molecular biology of the cell, Vol. 19, Issue 3, pp. 1072-82, (2008) (PubMed).

    Reuter, Medhurst, Waisfisz, Zhi, Herterich, Hoehn, Gross, Joenje, Hoatlin, Mathew, Huber: "Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport." in: Experimental cell research, Vol. 289, Issue 2, pp. 211-21, (2003) (PubMed).

  • 抗原

    USP14 (Ubiquitin Specific Peptidase 14 (USP14))

    别名

    USP14

    背景

    Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

    分子量

    56069

    NCBI登录号

    NP_001032411, NP_005142

    UniProt

    P54578
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