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Cytokeratin 18 抗体

There are 2+ publications for this product available. The 小鼠 单克隆 anti-Cytokeratin 18 antibody is suitable to detect Cytokeratin 18 in samples from 人. It has been validated for WB.
产品编号 ABIN1882229
发货至: 中国
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Quick Overview for Cytokeratin 18 抗体 (ABIN1882229)

抗原

See all Cytokeratin 18 (KRT18) 抗体
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Cytokeratin 18 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

695CT17-2-6
  • 纯化方法

    This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This CYK18 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 400-430 region of human CYK18.

    亚型

    IgG3
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Kulesh, Oshima: "Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells." in: Molecular and cellular biology, Vol. 8, Issue 4, pp. 1540-50, (1988) (PubMed).

    Oshima, Millán, Ceceña: "Comparison of mouse and human keratin 18: a component of intermediate filaments expressed prior to implantation." in: Differentiation; research in biological diversity, Vol. 33, Issue 1, pp. 61-8, (1987) (PubMed).

  • 抗原

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    别名

    CYK18

    背景

    Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

    分子量

    48058

    NCBI登录号

    NP_000215, NP_954657

    UniProt

    P05783

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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