Cytokeratin 18 抗体
Quick Overview for Cytokeratin 18 抗体 (ABIN1882229)
抗原
See all Cytokeratin 18 (KRT18) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This CYK18 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 400-430 region of human CYK18.
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亚型
- IgG3
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells." in: Molecular and cellular biology, Vol. 8, Issue 4, pp. 1540-50, (1988) (PubMed).
: "Comparison of mouse and human keratin 18: a component of intermediate filaments expressed prior to implantation." in: Differentiation; research in biological diversity, Vol. 33, Issue 1, pp. 61-8, (1987) (PubMed).
: "
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Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells." in: Molecular and cellular biology, Vol. 8, Issue 4, pp. 1540-50, (1988) (PubMed).
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- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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别名
- CYK18
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背景
- Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
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分子量
- 48058
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NCBI登录号
- NP_000215, NP_954657
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UniProt
- P05783
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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