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ACE2 抗体 (AA 1-270)

Cited in 3+ publications. This 小鼠 单克隆 anti-ACE2 antibody (Clone 881CT16-4-4) specifically detects ACE2 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1882201
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for ACE2 抗体 (AA 1-270) (ABIN1882201)

抗原

See all ACE2 抗体
ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ACE2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

881CT16-4-4
  • 抗原表位

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    AA 1-270

    纯化方法

    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

    免疫原

    Purified His-tagged ACE2 protein was used to produced this monoclonal antibody.

    亚型

    IgM
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Itoyama, Keicho, Hijikata, Quy, Phi, Long, Ha, Ban, Matsushita, Yanai, Kirikae, Kirikae, Kuratsuji, Sasazuki: "Identification of an alternative 5'-untranslated exon and new polymorphisms of angiotensin-converting enzyme 2 gene: lack of association with SARS in the Vietnamese population." in: American journal of medical genetics. Part A, Vol. 136, Issue 1, pp. 52-7, (2005) (PubMed).

    Douglas, OBryan, Hedger, Lee, Yarski, Smith, Lew: "The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis." in: Endocrinology, Vol. 145, Issue 10, pp. 4703-11, (2004) (PubMed).

    Tipnis, Hooper, Hyde, Karran, Christie, Turner: "A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase." in: The Journal of biological chemistry, Vol. 275, Issue 43, pp. 33238-43, (2000) (PubMed).

  • 抗原

    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

    背景

    Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

    分子量

    92463

    NCBI登录号

    NP_068576

    UniProt

    Q9BYF1

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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