ACE2 抗体 (AA 1-270)
Quick Overview for ACE2 抗体 (AA 1-270) (ABIN1882201)
抗原
See all ACE2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-270
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纯化方法
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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免疫原
- Purified His-tagged ACE2 protein was used to produced this monoclonal antibody.
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亚型
- IgM
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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Identification of an alternative 5'-untranslated exon and new polymorphisms of angiotensin-converting enzyme 2 gene: lack of association with SARS in the Vietnamese population." in: American journal of medical genetics. Part A, Vol. 136, Issue 1, pp. 52-7, (2005) (PubMed).
: "The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis." in: Endocrinology, Vol. 145, Issue 10, pp. 4703-11, (2004) (PubMed).
: "A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase." in: The Journal of biological chemistry, Vol. 275, Issue 43, pp. 33238-43, (2000) (PubMed).
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Identification of an alternative 5'-untranslated exon and new polymorphisms of angiotensin-converting enzyme 2 gene: lack of association with SARS in the Vietnamese population." in: American journal of medical genetics. Part A, Vol. 136, Issue 1, pp. 52-7, (2005) (PubMed).
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- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
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背景
- Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
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分子量
- 92463
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NCBI登录号
- NP_068576
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UniProt
- Q9BYF1
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
抗原
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