STK3 抗体 (AA 228-252)
Quick Overview for STK3 抗体 (AA 228-252) (ABIN1882187)
抗原
See all STK3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 228-252
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This DANRE stk3(36kDa subunit) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 228-252 amino acids from the Central region of DANRE stk3(36kDa subunit).
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anti-serine/threonine Kinase 3 (STK3) (AA 323-450) antibody
STK3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 1-491) antibodySTK3 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 311-431) antibodySTK3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-serine/threonine Kinase 3 (STK3) (C-Term) antibodySTK3 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 兔, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) antibodySTK3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (N-Term) antibodySTK3 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 兔, 马, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 396-425), (C-Term) antibodySTK3 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p) 宿主: 兔 Polyclonal RB1196 unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 253-350) antibodySTK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-serine/threonine Kinase 3 (STK3) (AA 1-491) antibodySTK3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-serine/threonine Kinase 3 (STK3) antibodySTK3 适用: 人, 猴, 犬 WB, IHC 宿主: 小鼠 Monoclonal 4G10 unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- STK3 (serine/threonine Kinase 3 (STK3))
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别名
- stk3
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背景
- Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein stk3/mst2 and stk4/mst1, in complex with its regulatory protein sav1, phosphorylates and activates lats1/2 in complex with its regulatory protein mob1, which in turn phosphorylates and inactivates yap1 oncoprotein and wwtr1/taz. Phosphorylation of yap1 by lats2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration (By similarity).
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分子量
- 56081
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UniProt
- Q7ZUQ3
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途径
- Tube Formation
抗原
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