CDC7 抗体 (N-Term)
Quick Overview for CDC7 抗体 (N-Term) (ABIN1882165)
抗原
See all CDC7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CDC7 (CDC7L1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDC7 (CDC7L1).
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Drf1, a novel regulatory subunit for human Cdc7 kinase." in: The EMBO journal, Vol. 21, Issue 12, pp. 3171-81, (2002) (PubMed).
: "A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines." in: Gene, Vol. 211, Issue 1, pp. 133-40, (1998) (PubMed).
: "Identification and characterization of a human protein kinase related to budding yeast Cdc7p." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 26, pp. 14320-5, (1998) (PubMed).
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: "Drf1, a novel regulatory subunit for human Cdc7 kinase." in: The EMBO journal, Vol. 21, Issue 12, pp. 3171-81, (2002) (PubMed).
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- CDC7 (Cell Division Cycle 7 (CDC7))
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别名
- CDC7 (CDC7L1)
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背景
- CDC7L1 is predominantly localized in the nucleus and is a cell division cycle protein with kinase activity. Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears to increase during S phase. It has been suggested that the protein is essential for initiation of DNA replication and that it plays a role in regulating cell cycle progression. Overexpression of this gene product may be associated with neoplastic transformation for some tumors.
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分子量
- 63888
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NCBI登录号
- NP_001127891, NP_001127892, NP_003494
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UniProt
- O00311
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途径
- Mitotic G1-G1/S Phases, DNA Replication
抗原
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