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CDC7 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects CDC7 in WB. It exhibits reactivity toward 人. It has been mentioned in 3+ publications
产品编号 ABIN1882165
发货至: 中国
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Quick Overview for CDC7 抗体 (N-Term) (ABIN1882165)

抗原

See all CDC7 抗体
CDC7 (Cell Division Cycle 7 (CDC7))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDC7 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB3541
  • 抗原表位

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    AA 1-30, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CDC7 (CDC7L1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDC7 (CDC7L1).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Montagnoli, Bosotti, Villa, Rialland, Brotherton, Mercurio, Berthelsen, Santocanale: "Drf1, a novel regulatory subunit for human Cdc7 kinase." in: The EMBO journal, Vol. 21, Issue 12, pp. 3171-81, (2002) (PubMed).

    Hess, Drong, Weiland, Slightom, Sclafani, Hollingsworth: "A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines." in: Gene, Vol. 211, Issue 1, pp. 133-40, (1998) (PubMed).

    Jiang, Hunter: "Identification and characterization of a human protein kinase related to budding yeast Cdc7p." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 26, pp. 14320-5, (1998) (PubMed).

  • 抗原

    CDC7 (Cell Division Cycle 7 (CDC7))

    别名

    CDC7 (CDC7L1)

    背景

    CDC7L1 is predominantly localized in the nucleus and is a cell division cycle protein with kinase activity. Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears to increase during S phase. It has been suggested that the protein is essential for initiation of DNA replication and that it plays a role in regulating cell cycle progression. Overexpression of this gene product may be associated with neoplastic transformation for some tumors.

    分子量

    63888

    NCBI登录号

    NP_001127891, NP_001127892, NP_003494

    UniProt

    O00311

    途径

    Mitotic G1-G1/S Phases, DNA Replication
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