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PLAU 抗体 (N-Term)

Name: PLAU 抗体 (N-Term)
SKU: ABIN1882148
Availability: OutOfStock

This anti-PLAU antibody is a 兔多克隆 antibody detecting PLAU in WB, FACS 和 IHC (p). Suitable for 人和小鼠. This Primary Antibody has been cited in 8+ publications.

Western blot analysis of anti-PLAU Antibody (N-term) (ABIN1882148 and ABIN2842233) in mouse brain tissue lysates (35 μg/lane). (PLAU 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with PLAU antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (PLAU 抗体 (N-Term))

IHC (p)

Western blot analysis of anti-PLAU Antibody (N-term) (ABIN1882148 and ABIN2842233) in cell line lysates (35 μg/lane). (PLAU 抗体 (N-Term))

Urokinase (PLAU) Antibody (N-term) (ABIN1882148 and ABIN2842233) flow cytometric analysis of cells (right histogram) compared to a negative control cell (left histogram). (PLAU 抗体 (N-Term))

FACS

4 images

(8 references)

产品编号 ABIN1882148

发货至: 中国

Quick Overview for PLAU 抗体 (N-Term) (ABIN1882148)

抗原

See all PLAU 抗体

PLAU (Plasminogen Activator, Urokinase (PLAU))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This PLAU antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB04087

抗原表位
7

6

6

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 60-90, N-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This Urokinase (PLAU) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-90 amino acids from the N-terminal region of human Urokinase (PLAU).

亚型

Ig Fraction
anti-Plasminogen Activator, Urokinase (PLAU) (C-Term) antibody
Verified PLAU 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Plasminogen Activator, Urokinase (PLAU) (AA 396-426) antibody
PLAU 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Plasminogen Activator, Urokinase (PLAU) (AA 60-90) antibody
PLAU 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Plasminogen Activator, Urokinase (PLAU) (AA 180-433) antibody
PLAU 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Plasminogen Activator, Urokinase (PLAU) (AA 16-115) antibody
PLAU 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B8 unconjugated

anti-Plasminogen Activator, Urokinase (PLAU) antibody
PLAU 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Plasminogen Activator, Urokinase (PLAU) (AA 396-426), (C-Term) antibody
PLAU 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB04089-04090 unconjugated

anti-Plasminogen Activator, Urokinase (PLAU) (AA 17-432) antibody
PLAU 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Plasminogen Activator, Urokinase (PLAU) (AA 21-173) antibody
PLAU 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Plasminogen Activator, Urokinase (PLAU) (AA 21-168) antibody
PLAU 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Kim, Minai-Tehrani, Kim, Shin, Hong, Kim, Lee, Chang, Yu, Bang, Cho, Yoon, Yu, Jiang, Cho: "Suppression of tumor growth in H-ras12V liver cancer mice by delivery of programmed cell death protein 4 using galactosylated poly(ethylene glycol)-chitosan-graft-spermine." in: Biomaterials, Vol. 33, Issue 6, pp. 1894-902, (2011) (PubMed).

Eefting, de Vries, Grimbergen, Karper, van Bockel, Quax et al.: "In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase ..." in: Journal of vascular surgery, Vol. 51, Issue 2, pp. 429-37, (2010) (PubMed).

Bacac, Migliavacca, Stehle, McKee, Delorenzi, Coindre, Guillou, Stamenkovic: "A gene expression signature that distinguishes desmoid tumours from nodular fasciitis." in: The Journal of pathology, Vol. 208, Issue 4, pp. 543-53, (2006) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Sperl, Jacob, Arroyo de Prada, Stürzebecher, Wilhelm, Bode, Magdolen, Huber, Moroder: "(4-aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 10, pp. 5113-8, (2000) (PubMed).

Türkmen, Schmitt, Schmalfeldt, Trommler, Hell, Creutzburg, Graeff, Magdolen: "Mutational analysis of the genes encoding urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in advanced ovarian cancer." in: Electrophoresis, Vol. 18, Issue 5, pp. 686-9, (1997) (PubMed).

Conne, Berczy, Belin: "Detection of polymorphisms in the human urokinase-type plasminogen activator gene." in: Thrombosis and haemostasis, Vol. 77, Issue 3, pp. 434-5, (1997) (PubMed).

Yoshimoto, Ushiyama, Sakai, Tamaki, Hara, Takahashi, Sawasaki, Hanada: "Characterization of single chain urokinase-type plasminogen activator with a novel amino-acid substitution in the kringle structure." in: Biochimica et biophysica acta, Vol. 1293, Issue 1, pp. 83-9, (1996) (PubMed).
抗原

PLAU (Plasminogen Activator, Urokinase (PLAU))

背景

PLAU, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders. PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin. The protein is found in high and low molecular mass forms. Each consists of two chains, A and B. The high molecular mass form contains a long chain A. Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain. The protein is used in Pulmonary Embolism (PE) to initiates fibrinolysis. Structurally, PLAU contains 1 EGF-like domain and 1 kringle domain.

分子量

48507

NCBI登录号

NP_001138503, NP_002649

UniProt

P00749

途径

Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration