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SSB 抗体 (N-Term)

There are 3+ publications for this product available. The 兔 多克隆 anti-SSB antibody is suitable to detect SSB in samples from 人. It has been validated for WB, IHC (p) 和 FACS.
产品编号 ABIN1882133
发货至: 中国
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Quick Overview for SSB 抗体 (N-Term) (ABIN1882133)

抗原

See all SSB 抗体
SSB (Sjogren Syndrome Antigen B (SSB))

适用

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宿主

  • 73
  • 15
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克隆类型

  • 80
  • 13
多克隆

标记

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This SSB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB17351
  • 抗原表位

    • 15
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    AA 66-96, N-Term

    预测反应

    B

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This SSB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human SSB.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Nitta, Tam, Kim, Fan: "The cellular protein La functions in enhancement of virus release through lipid rafts facilitated by murine leukemia virus glycosylated Gag." in: mBio, Vol. 2, Issue 1, pp. e00341-10, (2011) (PubMed).

    Bitko, Musiyenko, Bayfield, Maraia, Barik: "Cellular La protein shields nonsegmented negative-strand RNA viral leader RNA from RIG-I and enhances virus growth by diverse mechanisms." in: Journal of virology, Vol. 82, Issue 16, pp. 7977-87, (2008) (PubMed).

    Kotik-Kogan, Valentine, Sanfelice, Conte, Curry: "Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human La protein." in: Structure (London, England : 1993), Vol. 16, Issue 6, pp. 852-62, (2008) (PubMed).

  • 抗原

    SSB (Sjogren Syndrome Antigen B (SSB))

    别名

    SSB

    背景

    SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III -transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. This protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.

    分子量

    46837

    NCBI登录号

    NP_003133

    UniProt

    P05455
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