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FAK 抗体 (AA 396-423)

Cited in 2+ publications. This 兔 多克隆 anti-FAK antibody (Clone RB20775) specifically detects FAK in WB, IF, IHC (p) 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN1882121
发货至: 中国
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Quick Overview for FAK 抗体 (AA 396-423) (ABIN1882121)

抗原

See all FAK (PTK2) 抗体
FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

适用

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宿主

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克隆类型

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多克隆

标记

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This FAK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB20775
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    AA 396-423

    预测反应

    C, M, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This PTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the Central region of human PTK2.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Stowe, Turlings, Loughrin, Lewis, Tumlinson: "The chemistry of eavesdropping, alarm, and deceit." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 1, pp. 23-8, (1995) (PubMed).

    Calalb, Polte, Hanks: "Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases." in: Molecular and cellular biology, Vol. 15, Issue 2, pp. 954-63, (1995) (PubMed).

  • 抗原

    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

    别名

    PTK2

    背景

    PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

    分子量

    119233

    NCBI登录号

    NP_001186578, NP_722560

    UniProt

    Q05397

    途径

    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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