FKBP1A 抗体 (C-Term)
(2 references)Quick Overview for FKBP1A 抗体 (C-Term) (ABIN1882082)
抗原
See all FKBP1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 55-83, C-Term
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预测反应
- B, Rb
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This FKBP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the C-terminal region of human FKBP1A.
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亚型
- Ig Fraction
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anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 1-108) antibody
FKBP1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E5-A12 unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 1-108) antibodyFKBP1A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-103) antibodyFKBP1A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) antibodyFKBP1A 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-108) antibodyFKBP1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-108) antibodyFKBP1A 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal E3 unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (N-Term) antibodyFKBP1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) antibodyFKBP1A 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 43-74) antibodyFKBP1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) antibodyFKBP1A 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T." in: Journal of neurochemistry, Vol. 106, Issue 1, pp. 121-33, (2008) (PubMed).
: "A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis." in: Cancer research, Vol. 68, Issue 8, pp. 2934-43, (2008) (PubMed).
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: "FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T." in: Journal of neurochemistry, Vol. 106, Issue 1, pp. 121-33, (2008) (PubMed).
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- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
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别名
- FKBP1A
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背景
- FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
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分子量
- 11951
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NCBI登录号
- NP_000792, NP_463460
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UniProt
- P62942
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途径
- Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
抗原
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