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FDPS 抗体 (N-Term)

This anti-FDPS antibody is a 兔 多克隆 antibody detecting FDPS in WB, IHC (p) 和 IF. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1882080
发货至: 中国

Quick Overview for FDPS 抗体 (N-Term) (ABIN1882080)

抗原

See all FDPS 抗体
FDPS (Farnesyl Diphosphate Synthase (FDPS))

适用

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宿主

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克隆类型

  • 47
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多克隆

标记

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This FDPS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

克隆位点

RB4783-4784
  • 抗原表位

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    AA 82-112, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This FDPS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-112 amino acids from the N-terminal region of human FDPS.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:100. WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Wilkin, Kutsunai, Edwards et al.: "Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, ..." in: The Journal of biological chemistry, Vol. 265, Issue 8, pp. 4607-14, (1990) (PubMed).

    Sheares, White, Molowa, Chan, Ding, Kroon, Bostedor, Karkas: "Cloning, analysis, and bacterial expression of human farnesyl pyrophosphate synthetase and its regulation in Hep G2 cells." in: Biochemistry, Vol. 28, Issue 20, pp. 8129-35, (1990) (PubMed).

  • 抗原

    FDPS (Farnesyl Diphosphate Synthase (FDPS))

    别名

    FDPS

    背景

    The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes.1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.

    分子量

    48275

    NCBI登录号

    NP_001129293, NP_001129294, NP_001229753, NP_001229754, NP_001995

    UniProt

    P14324

    途径

    Regulation of Muscle Cell Differentiation
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