BBS4 抗体 (AA 1-240)
(1 reference)Quick Overview for BBS4 抗体 (AA 1-240) (ABIN1882046)
抗原
See all BBS4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-240
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This BBS4 antibody is generated from a mice immunized with a recombinant protein between 1-240 amino acids from human BBS4.
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亚型
- IgG1
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anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 350-519) antibody
BBS4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-519) antibodyBBS4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 431-519) antibodyBBS4 适用: 小鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (N-Term) antibodyBBS4 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Pig, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-519) antibodyBBS4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 215-264) antibodyBBS4 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 兔, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 71-120) antibodyBBS4 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 33-46) antibodyVerified BBS4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 125-139) antibodyVerified BBS4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 337-369) antibodyBBS4 适用: 人 WB 宿主: 兔 Polyclonal RB14682 unconjugated
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应用备注
- IHC: 1:250. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Dissection of epistasis in oligogenic Bardet-Biedl syndrome." in: Nature, Vol. 439, Issue 7074, pp. 326-30, (2006) (PubMed).
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: "Dissection of epistasis in oligogenic Bardet-Biedl syndrome." in: Nature, Vol. 439, Issue 7074, pp. 326-30, (2006) (PubMed).
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- BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
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别名
- BBS4
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背景
- The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization. Required for microtubule anchoring at the centrosome but not for microtubule nucleation. May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome.
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分子量
- 58282
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UniProt
- Q96RK4
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途径
- Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
抗原
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