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Vimentin 抗体

Cited in 3+ publications. The 兔 多克隆 anti-Vimentin antibody (Clone RB41034) (ABIN1881993) specifically detects Vimentin in WB, IF, FACS 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1881993
发货至: 中国
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Quick Overview for Vimentin 抗体 (ABIN1881993)

抗原

See all Vimentin (VIM) 抗体
Vimentin (VIM)

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Vimentin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB41034
  • 纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Vimentin antibody is generated from rabbits immunized with human Vimentin recombinant protein.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:50. IF: 1:50. IF: 1:50. WB: 1:4000. WB: 1:2000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Fuechsle, Mahapatra, Zwanenburg, Friesen, Eriksson, Simmons: "Spectroscopy of few-electron single-crystal silicon quantum dots." in: Nature nanotechnology, Vol. 5, Issue 7, pp. 502-5, (2010) (PubMed).

    Li, Zhang, Sun, Wang, Ban, Sun, Liu, Zhao: "A novel function for vimentin: the potential biomarker for predicting melanoma hematogenous metastasis." in: Journal of experimental & clinical cancer research : CR, Vol. 29, pp. 109, (2010) (PubMed).

    Korita, Wakai, Ajioka, Inoue, Takamura, Shirai, Hatakeyama: "Aberrant expression of vimentin correlates with dedifferentiation and poor prognosis in patients with intrahepatic cholangiocarcinoma." in: Anticancer research, Vol. 30, Issue 6, pp. 2279-85, (2010) (PubMed).

  • 抗原

    Vimentin (VIM)

    别名

    Vimentin

    背景

    This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.

    分子量

    53652

    NCBI登录号

    NP_003371

    UniProt

    P08670

    途径

    Caspase Cascade in Apoptosis
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