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ULK1 抗体 (pSer467)

This anti-ULK1 antibody is a 兔 多克隆 antibody detecting ULK1 in DB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1881981
发货至: 中国

Quick Overview for ULK1 抗体 (pSer467) (ABIN1881981)

抗原

See all ULK1 抗体
ULK1 (Unc-51 Like Kinase 1 (ULK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ULK1 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB30636
  • 抗原表位

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    pSer467

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ULK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S467 of human ULK1.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Mercer, Kaliappan, Dennis: "A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy." in: Autophagy, Vol. 5, Issue 5, pp. 649-62, (2009) (PubMed).

    Ganley, Lam, Wang, Ding, Chen, Jiang: "ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy." in: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 12297-305, (2009) (PubMed).

    Jung, Jun, Ro, Kim, Otto, Cao, Kundu, Kim: "ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1992-2003, (2009) (PubMed).

    Hosokawa, Hara, Kaizuka, Kishi, Takamura, Miura, Iemura, Natsume, Takehana, Yamada, Guan, Oshiro, Mizushima: "Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1981-91, (2009) (PubMed).

  • 抗原

    ULK1 (Unc-51 Like Kinase 1 (ULK1))

    别名

    ULK1

    背景

    ULK1 is involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity).

    分子量

    112631

    NCBI登录号

    NP_003556

    UniProt

    O75385

    途径

    Regulation of Cell Size, Autophagy
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