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ULK1 抗体 (pSer556)

This anti-ULK1 antibody is a 兔 多克隆 antibody detecting ULK1 in DB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1881980
发货至: 中国

Quick Overview for ULK1 抗体 (pSer556) (ABIN1881980)

抗原

See all ULK1 抗体
ULK1 (Unc-51 Like Kinase 1 (ULK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ULK1 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB40759
  • 抗原表位

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    pSer556

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ULK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S556 of human ULK1.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Mercer, Kaliappan, Dennis: "A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy." in: Autophagy, Vol. 5, Issue 5, pp. 649-62, (2009) (PubMed).

    Ganley, Lam, Wang, Ding, Chen, Jiang: "ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy." in: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 12297-305, (2009) (PubMed).

    Jung, Jun, Ro, Kim, Otto, Cao, Kundu, Kim: "ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1992-2003, (2009) (PubMed).

    Hosokawa, Hara, Kaizuka, Kishi, Takamura, Miura, Iemura, Natsume, Takehana, Yamada, Guan, Oshiro, Mizushima: "Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1981-91, (2009) (PubMed).

  • 抗原

    ULK1 (Unc-51 Like Kinase 1 (ULK1))

    别名

    ULK1

    背景

    Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity).

    分子量

    112631

    NCBI登录号

    NP_003556

    UniProt

    O75385

    途径

    Regulation of Cell Size, Autophagy
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