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ULK1 抗体 (pSer556)

Cited in 3+ publications. This anti-ULK1 antibody is a 兔 多克隆 antibody detecting ULK1 in DB 和 IF. Suitable for 人.
产品编号 ABIN1881979
发货至: 中国
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Quick Overview for ULK1 抗体 (pSer556) (ABIN1881979)

抗原

See all ULK1 抗体
ULK1 (Unc-51 Like Kinase 1 (ULK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ULK1 antibody is un-conjugated

应用范围

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Dot Blot (DB), Immunofluorescence (IF)

克隆位点

RB30585
  • 抗原表位

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    pSer556

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ULK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S556 of human ULK1.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:200. DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Geng, Kohli, Klocke, Roth: "Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent." in: Neuro-oncology, Vol. 12, Issue 5, pp. 473-81, (2010) (PubMed).

    Pontén, Westermark: "Properties of human malignant glioma cells in vitro." in: Medical biology, Vol. 56, Issue 4, pp. 184-93, (1978) (PubMed).

    Westermark, Pontén, Hugosson: "Determinants for the establishment of permanent tissue culture lines from human gliomas." in: Acta pathologica et microbiologica Scandinavica. Section A, Pathology, Vol. 81, Issue 6, pp. 791-805, (1974) (PubMed).

  • 抗原

    ULK1 (Unc-51 Like Kinase 1 (ULK1))

    别名

    ULK1

    背景

    Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity).

    分子量

    112631

    NCBI登录号

    NP_003556

    UniProt

    O75385

    途径

    Regulation of Cell Size, Autophagy
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