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UBE2S 抗体 (C-Term)

There are 5+ publications for this product available. The 兔 多克隆 anti-UBE2S antibody is suitable to detect UBE2S in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN1881968
发货至: 中国
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Quick Overview for UBE2S 抗体 (C-Term) (ABIN1881968)

抗原

See all UBE2S 抗体
UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))

适用

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宿主

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克隆类型

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多克隆

标记

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This UBE2S antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB42367
  • 抗原表位

    • 8
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    AA 183-210, C-Term

    预测反应

    X, B, M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This UBE2S antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-210 amino acids from the C-terminal region of human UBE2S.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Wu, Merbl, Huo, Gallop, Tzur, Kirschner: "UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 4, pp. 1355-60, (2010) (PubMed).

    Williamson, Wickliffe, Mellone, Song, Karpen, Rape: "Identification of a physiological E2 module for the human anaphase-promoting complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 43, pp. 18213-8, (2009) (PubMed).

    Chen, Lee, Lu, Chen, Hsieh, Liu, Lin, Chen: "The predictive role of E2-EPF ubiquitin carrier protein in esophageal squamous cell carcinoma." in: Journal of molecular medicine (Berlin, Germany), Vol. 87, Issue 3, pp. 307-20, (2009) (PubMed).

    Garnett, Mansfeld, Godwin, Matsusaka, Wu, Russell, Pines, Venkitaraman: "UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit." in: Nature cell biology, Vol. 11, Issue 11, pp. 1363-9, (2009) (PubMed).

    Lim, Jung, Lee, Im: "Egr-1 and serum response factor are involved in growth factors- and serum-mediated induction of E2-EPF UCP expression that regulates the VHL-HIF pathway." in: Journal of cellular biochemistry, Vol. 105, Issue 4, pp. 1117-27, (2008) (PubMed).

  • 抗原

    UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))

    别名

    UBE2S

    背景

    This gene encodes a member of the ubiquitin-conjugating enzyme family. The encoded protein is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme-dependent manner, a characteristic property of ubiquitin carrier proteins.

    分子量

    23845

    NCBI登录号

    NP_055316

    UniProt

    Q16763

    途径

    Ubiquitin Proteasome Pathway
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