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Tuberin 抗体 (pThr1373)

TSC2 适用: 大鼠 DB 宿主: 兔 Polyclonal RB41276 unconjugated
产品编号 ABIN1881935
发货至: 中国
  • 抗原 See all Tuberin (TSC2) 抗体
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    抗原表位
    • 29
    • 22
    • 20
    • 19
    • 16
    • 16
    • 15
    • 15
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    • 13
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr1373
    适用
    • 285
    • 188
    • 123
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 376
    • 12
    克隆类型
    • 367
    • 21
    多克隆
    标记
    • 143
    • 34
    • 33
    • 31
    • 24
    • 23
    • 11
    • 11
    • 11
    • 11
    • 10
    • 10
    • 7
    • 7
    • 7
    • 7
    • 7
    • 1
    This Tuberin antibody is un-conjugated
    应用范围
    • 212
    • 177
    • 124
    • 81
    • 80
    • 59
    • 36
    • 34
    • 20
    • 12
    • 9
    • 7
    • 6
    • 4
    • 2
    Dot Blot (DB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This rat TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1373 of rat TSC2.
    克隆位点
    RB41276
    亚型
    Ig Fraction
    Top Product
    Discover our top product TSC2 Primary Antibody
  • 应用备注
    DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Larson, Liu, Stevens, Li, Li, Evers, Gao: "Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24987-98, (2010) (PubMed).

    Di Nardo, Kramvis, Cho, Sadowski, Meikle, Kwiatkowski, Sahin: "Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 18, pp. 5926-37, (2009) (PubMed).

    Shiono, Kobayashi, Takahashi, Sun, Abe, Zhang, Wang, Piao, Takagi, Mineki, Taka, Tada, Sonobe, Momose, Ueda, Hino: "The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition." in: Oncogene, Vol. 27, Issue 52, pp. 6690-7, (2008) (PubMed).

  • 抗原
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    别名
    TSC2 (TSC2 产品)
    别名
    TSC2 antibody, fc16b02 antibody, tuberin antibody, wu:fc16b02 antibody, LAM antibody, TSC4 antibody, Nafld antibody, Tcs2 antibody, Rc antibody, TSC complex subunit 2 antibody, tuberin antibody, hypothetical protein antibody, tuberous sclerosis 2 antibody, TSC2 antibody, LOC5569538 antibody, tsc2 antibody, PGTG_00159 antibody, Tsc2 antibody
    背景
    Acts as a tumor suppressor, may play a role in cell cycle regulation, acute phase response, and negative regulation of cell proliferation [RGD].
    分子量
    201278
    NCBI登录号
    NP_036812
    UniProt
    P49816
    途径
    RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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