电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TSC1 抗体 (pTyr312)

Cited in 5+ publications. This anti-TSC1 antibody is a 兔 多克隆 antibody detecting TSC1 in DB. Suitable for 人.
产品编号 ABIN1881934
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TSC1 抗体 (pTyr312) (ABIN1881934)

抗原

See all TSC1 抗体
TSC1 (Tuberous Sclerosis 1 (TSC1))

适用

  • 198
  • 139
  • 52
  • 24
  • 18
  • 2
  • 1
  • 1

宿主

  • 312
  • 16
  • 1
  • 1

克隆类型

  • 305
  • 25
多克隆

标记

  • 115
  • 37
  • 37
  • 36
  • 32
  • 32
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TSC1 antibody is un-conjugated

应用范围

  • 231
  • 206
  • 104
  • 41
  • 27
  • 26
  • 26
  • 21
  • 15
  • 14
  • 7
  • 6
  • 3
  • 1
Dot Blot (DB)

克隆位点

RB42255
  • 抗原表位

    • 24
    • 16
    • 16
    • 16
    • 15
    • 14
    • 14
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr312

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y312 of human TSC1.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Mehta, Vazquez, Kulkarni, Kerrigan, Atwal, Metsugi, Toppmeyer, Levine, Hirshfield: "Polymorphic variants in TSC1 and TSC2 and their association with breast cancer phenotypes." in: Breast cancer research and treatment, Vol. 125, Issue 3, pp. 861-8, (2011) (PubMed).

    Hoogeveen-Westerveld, Exalto, Maat-Kievit, van den Ouweland, Halley, Nellist: "Analysis of TSC1 truncations defines regions involved in TSC1 stability, aggregation and interaction." in: Biochimica et biophysica acta, Vol. 1802, Issue 9, pp. 774-81, (2010) (PubMed).

    Mieulet, Lamb: "Tuberous sclerosis complex: linking cancer to metabolism." in: Trends in molecular medicine, Vol. 16, Issue 7, pp. 329-35, (2010) (PubMed).

    Guo, Ying, Zhang, Yuan, Qian, Wang, Yang, He: "Tandem affinity purification and identification of the human TSC1 protein complex." in: Acta biochimica et biophysica Sinica, Vol. 42, Issue 4, pp. 266-73, (2010) (PubMed).

    Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

  • 抗原

    TSC1 (Tuberous Sclerosis 1 (TSC1))

    别名

    TSC1

    背景

    This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.

    分子量

    129767

    NCBI登录号

    NP_000359, NP_001155898, NP_001155899

    UniProt

    Q92574

    途径

    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
You are here: