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TSC1 抗体 (pThr519)

TSC1 适用: 人 DB 宿主: 兔 Polyclonal RB42205 unconjugated
产品编号 ABIN1881931
发货至: 中国
  • 抗原 See all TSC1 抗体
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    抗原表位
    • 24
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr519
    适用
    • 187
    • 139
    • 53
    • 24
    • 18
    • 2
    • 1
    • 1
    宿主
    • 301
    • 16
    • 1
    • 1
    克隆类型
    • 303
    • 16
    多克隆
    标记
    • 113
    • 37
    • 36
    • 36
    • 32
    • 32
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This TSC1 antibody is un-conjugated
    应用范围
    • 230
    • 207
    • 92
    • 28
    • 26
    • 26
    • 16
    • 14
    • 9
    • 7
    • 6
    • 4
    • 3
    • 1
    Dot Blot (DB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T519 of human TSC1.
    克隆位点
    RB42205
    亚型
    Ig Fraction
    Top Product
    Discover our top product TSC1 Primary Antibody
  • 应用备注
    DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Mehta, Vazquez, Kulkarni, Kerrigan, Atwal, Metsugi, Toppmeyer, Levine, Hirshfield: "Polymorphic variants in TSC1 and TSC2 and their association with breast cancer phenotypes." in: Breast cancer research and treatment, Vol. 125, Issue 3, pp. 861-8, (2011) (PubMed).

    Hoogeveen-Westerveld, Exalto, Maat-Kievit, van den Ouweland, Halley, Nellist: "Analysis of TSC1 truncations defines regions involved in TSC1 stability, aggregation and interaction." in: Biochimica et biophysica acta, Vol. 1802, Issue 9, pp. 774-81, (2010) (PubMed).

    Mieulet, Lamb: "Tuberous sclerosis complex: linking cancer to metabolism." in: Trends in molecular medicine, Vol. 16, Issue 7, pp. 329-35, (2010) (PubMed).

    Guo, Ying, Zhang, Yuan, Qian, Wang, Yang, He: "Tandem affinity purification and identification of the human TSC1 protein complex." in: Acta biochimica et biophysica Sinica, Vol. 42, Issue 4, pp. 266-73, (2010) (PubMed).

    Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

  • 抗原
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    别名
    TSC1 (TSC1 产品)
    别名
    LAM antibody, TSC antibody, hamartin antibody, mKIAA0243 antibody, tsc1 antibody, wu:fc38b04 antibody, fa99f04 antibody, wu:fa99f04 antibody, zgc:63657 antibody, TSC complex subunit 1 antibody, tuberous sclerosis 1 antibody, TSC complex subunit 1b antibody, TSC complex subunit 1a antibody, TSC1 antibody, Tsc1 antibody, tsc1b antibody, tsc1 antibody, tsc1a antibody
    背景
    This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.
    分子量
    129767
    NCBI登录号
    NP_000359, NP_001155898, NP_001155899
    UniProt
    Q92574
    途径
    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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