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TSC1 抗体 (pThr310)

This anti-TSC1 antibody is a 兔 多克隆 antibody detecting TSC1 in DB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1881928
发货至: 中国

Quick Overview for TSC1 抗体 (pThr310) (ABIN1881928)

抗原

See all TSC1 抗体
TSC1 (Tuberous Sclerosis 1 (TSC1))

适用

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宿主

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克隆类型

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  • 17
多克隆

标记

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This TSC1 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB42049
  • 抗原表位

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    pThr310

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T310 of human TSC1.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Mehta, Vazquez, Kulkarni, Kerrigan, Atwal, Metsugi, Toppmeyer, Levine, Hirshfield: "Polymorphic variants in TSC1 and TSC2 and their association with breast cancer phenotypes." in: Breast cancer research and treatment, Vol. 125, Issue 3, pp. 861-8, (2011) (PubMed).

    Hoogeveen-Westerveld, Exalto, Maat-Kievit, van den Ouweland, Halley, Nellist: "Analysis of TSC1 truncations defines regions involved in TSC1 stability, aggregation and interaction." in: Biochimica et biophysica acta, Vol. 1802, Issue 9, pp. 774-81, (2010) (PubMed).

    Mieulet, Lamb: "Tuberous sclerosis complex: linking cancer to metabolism." in: Trends in molecular medicine, Vol. 16, Issue 7, pp. 329-35, (2010) (PubMed).

    Guo, Ying, Zhang, Yuan, Qian, Wang, Yang, He: "Tandem affinity purification and identification of the human TSC1 protein complex." in: Acta biochimica et biophysica Sinica, Vol. 42, Issue 4, pp. 266-73, (2010) (PubMed).

    Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

  • 抗原

    TSC1 (Tuberous Sclerosis 1 (TSC1))

    别名

    TSC1

    背景

    This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.

    分子量

    129767

    NCBI登录号

    NP_000359, NP_001155898, NP_001155899

    UniProt

    Q92574

    途径

    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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