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TSC1 抗体 (AA 395-424)

This anti-TSC1 antibody is a 兔 多克隆 antibody detecting TSC1 in WB. Suitable for 人.
产品编号 ABIN1881924
发货至: 中国
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Quick Overview for TSC1 抗体 (AA 395-424) (ABIN1881924)

抗原

See all TSC1 抗体
TSC1 (Tuberous Sclerosis 1 (TSC1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TSC1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB42204
  • 抗原表位

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    AA 395-424

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the Central region of human TSC1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    TSC1 (Tuberous Sclerosis 1 (TSC1))

    别名

    TSC1

    背景

    In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

    分子量

    129767

    NCBI登录号

    NP_000359, NP_001155898, NP_001155899

    UniProt

    Q92574

    途径

    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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