TSC1 抗体 (pThr416)
Quick Overview for TSC1 抗体 (pThr416) (ABIN1881922)
抗原
See all TSC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- pThr416
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T416 of mouse TSC1.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- DB: 1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
-
: "Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." in: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).
: "Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice." in: Cancer research, Vol. 70, Issue 21, pp. 8937-47, (2010) (PubMed).
-
: "Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." in: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).
-
- TSC1 (Tuberous Sclerosis 1 (TSC1))
-
别名
- TSC1
-
背景
- In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
-
分子量
- 128746
-
NCBI登录号
- NP_075025
-
UniProt
- Q9EP53
-
途径
- RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
抗原
-