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TSC1 抗体 (pThr416)

Cited in 2+ publications. This 兔 多克隆 anti-TSC1 antibody (Clone RB42189) specifically detects TSC1 in DB. The antibody is reactive with 小鼠 samples.
产品编号 ABIN1881922
发货至: 中国
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Quick Overview for TSC1 抗体 (pThr416) (ABIN1881922)

抗原

See all TSC1 抗体
TSC1 (Tuberous Sclerosis 1 (TSC1))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This TSC1 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB42189
  • 抗原表位

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    pThr416

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T416 of mouse TSC1.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Akpa, Oyejola: "Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." in: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).

    Kladney, Cardiff, Kwiatkowski, Chiang, Weber, Arbeit, Lu: "Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice." in: Cancer research, Vol. 70, Issue 21, pp. 8937-47, (2010) (PubMed).

  • 抗原

    TSC1 (Tuberous Sclerosis 1 (TSC1))

    别名

    TSC1

    背景

    In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).

    分子量

    128746

    NCBI登录号

    NP_075025

    UniProt

    Q9EP53

    途径

    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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