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TSC1 抗体 (pTyr297)

TSC1 适用: 大鼠 DB 宿主: 兔 Polyclonal RB41272 unconjugated
产品编号 ABIN1881909
发货至: 中国
  • 抗原 See all TSC1 抗体
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    抗原表位
    • 24
    • 16
    • 16
    • 16
    • 15
    • 14
    • 13
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
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    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr297
    适用
    • 188
    • 139
    • 52
    • 24
    • 18
    • 2
    • 1
    • 1
    大鼠
    宿主
    • 301
    • 16
    • 1
    • 1
    克隆类型
    • 303
    • 16
    多克隆
    标记
    • 113
    • 37
    • 36
    • 36
    • 32
    • 32
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This TSC1 antibody is un-conjugated
    应用范围
    • 230
    • 207
    • 92
    • 28
    • 26
    • 26
    • 16
    • 14
    • 9
    • 7
    • 6
    • 4
    • 3
    • 1
    Dot Blot (DB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This rat TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y297 of rat TSC1.
    克隆位点
    RB41272
    亚型
    Ig Fraction
    Top Product
    Discover our top product TSC1 Primary Antibody
  • 应用备注
    DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Inoue, Ndong, Suzuki, Kazami, Uyama, Kobayashi, Tadokoro, Yamamoto: "Hamartin-Hsp70 interaction is necessary for Akt-dependent tuberin phosphorylation during heat shock." in: Bioscience, biotechnology, and biochemistry, Vol. 73, Issue 11, pp. 2488-93, (2009) (PubMed).

    Di Nardo, Kramvis, Cho, Sadowski, Meikle, Kwiatkowski, Sahin: "Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 18, pp. 5926-37, (2009) (PubMed).

    Chen, Yan, Chen, He: "The variation of AkT/TSC1-TSC1/mTOR signal pathway in hepatocytes after partial hepatectomy in rats." in: Experimental and molecular pathology, Vol. 86, Issue 2, pp. 101-7, (2009) (PubMed).

    Momose, Kobayashi, Tada, Itoyama, Hino: "N-terminal hamartin-binding and C-terminal GAP domain of tuberin can separate in vivo." in: Biochemical and biophysical research communications, Vol. 356, Issue 3, pp. 693-8, (2007) (PubMed).

  • 抗原
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    别名
    TSC1 (TSC1 产品)
    别名
    LAM antibody, TSC antibody, hamartin antibody, mKIAA0243 antibody, tsc1 antibody, wu:fc38b04 antibody, fa99f04 antibody, wu:fa99f04 antibody, zgc:63657 antibody, TSC complex subunit 1 antibody, tuberous sclerosis 1 antibody, TSC complex subunit 1b antibody, TSC complex subunit 1a antibody, TSC1 antibody, Tsc1 antibody, tsc1b antibody, tsc1 antibody, tsc1a antibody
    背景
    In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
    分子量
    129022
    NCBI登录号
    NP_068626
    UniProt
    Q9Z136
    途径
    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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