TSC1 抗体 (pSer1141)
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北京 101111
Quick Overview for TSC1 抗体 (pSer1141) (ABIN1881906)
抗原
See all TSC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer1141
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This rat TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1141 of rat TSC1.
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亚型
- Ig Fraction
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anti-Tuberous Sclerosis 1 (TSC1) (AA 550-650) antibody
TSC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibodyTSC1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A2 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (C-Term) antibodyTSC1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibodyTSC1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5A8 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) antibodyTSC1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibodyTSC1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (C-Term) antibodyTSC1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (pSer505) antibodyTSC1 适用: 人, 小鼠, 绵羊 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 101-344) antibodyTSC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibodyTSC1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB11648 unconjugated
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应用备注
- DB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Hamartin-Hsp70 interaction is necessary for Akt-dependent tuberin phosphorylation during heat shock." in: Bioscience, biotechnology, and biochemistry, Vol. 73, Issue 11, pp. 2488-93, (2009) (PubMed).
: "Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 18, pp. 5926-37, (2009) (PubMed).
: "The variation of AkT/TSC1-TSC1/mTOR signal pathway in hepatocytes after partial hepatectomy in rats." in: Experimental and molecular pathology, Vol. 86, Issue 2, pp. 101-7, (2009) (PubMed).
: "N-terminal hamartin-binding and C-terminal GAP domain of tuberin can separate in vivo." in: Biochemical and biophysical research communications, Vol. 356, Issue 3, pp. 693-8, (2007) (PubMed).
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: "Hamartin-Hsp70 interaction is necessary for Akt-dependent tuberin phosphorylation during heat shock." in: Bioscience, biotechnology, and biochemistry, Vol. 73, Issue 11, pp. 2488-93, (2009) (PubMed).
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- TSC1 (Tuberous Sclerosis 1 (TSC1))
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别名
- TSC1
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背景
- In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
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分子量
- 129022
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NCBI登录号
- NP_068626
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UniProt
- Q9Z136
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途径
- RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
抗原
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