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RRM1 抗体 (N-Term)

There are 2+ publications for this product available. The 兔 多克隆 anti-RRM1 antibody is suitable to detect RRM1 in samples from 人. It has been validated for WB.
产品编号 ABIN1881767
发货至: 中国
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Quick Overview for RRM1 抗体 (N-Term) (ABIN1881767)

抗原

See all RRM1 抗体
RRM1 (Ribonucleotide Reductase M1 (RRM1))

适用

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宿主

  • 92
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克隆类型

  • 70
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多克隆

标记

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This RRM1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB42407
  • 抗原表位

    • 15
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    AA 71-100, N-Term

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human RRM1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Ucisik-Akkaya, Davis, Do, Morrison, Stemmer, Amadio, Dorak: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).

    Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

  • 抗原

    RRM1 (Ribonucleotide Reductase M1 (RRM1))

    别名

    RRM1

    背景

    This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

    分子量

    90070

    NCBI登录号

    NP_001024

    UniProt

    P23921

    途径

    Positive Regulation of Endopeptidase Activity
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