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RPS6KA1 抗体 (pThr359)

Cited in 4+ publications. This anti-RPS6KA1 antibody is a 兔 多克隆 antibody detecting RPS6KA1 in WB 和 DB. Suitable for 人.
产品编号 ABIN1881765
发货至: 中国
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Quick Overview for RPS6KA1 抗体 (pThr359) (ABIN1881765)

抗原

See all RPS6KA1 抗体
RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

适用

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宿主

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克隆类型

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多克隆

标记

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This RPS6KA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Dot Blot (DB)

克隆位点

RB13385
  • 抗原表位

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    pThr359

    预测反应

    C, X

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RPS6KA1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T359 of human RPS6KA1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Roux, Ballif, Anjum, Gygi, Blenis: "Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 37, pp. 13489-94, (2004) (PubMed).

    Bohuslav, Chen, Kwon, Mu, Greene: "p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26115-25, (2004) (PubMed).

    Hu, Fang, Dunham, Prada, Stachowiak, Stachowiak: "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling." in: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29325-35, (2004) (PubMed).

    Fernando, Wimalasena: "Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt." in: Molecular biology of the cell, Vol. 15, Issue 7, pp. 3266-84, (2004) (PubMed).

  • 抗原

    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

    别名

    RPS6KA1

    背景

    RPS6KA1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation.

    分子量

    82723

    NCBI登录号

    NP_001006666, NP_002944

    UniProt

    Q15418

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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