电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

RPS6KA1 抗体 (pThr359)

This anti-RPS6KA1 antibody is a 兔 多克隆 antibody detecting RPS6KA1 in WB 和 DB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1881765
发货至: 中国

Quick Overview for RPS6KA1 抗体 (pThr359) (ABIN1881765)

抗原

See all RPS6KA1 抗体
RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

适用

  • 189
  • 102
  • 74
  • 6
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 195
  • 17

克隆类型

  • 169
  • 44
多克隆

标记

  • 104
  • 13
  • 12
  • 10
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
This RPS6KA1 antibody is un-conjugated

应用范围

  • 171
  • 93
  • 54
  • 53
  • 49
  • 25
  • 24
  • 20
  • 12
  • 11
  • 8
  • 2
  • 2
  • 2
Western Blotting (WB), Dot Blot (DB)

克隆位点

RB13385
  • 抗原表位

    • 32
    • 22
    • 19
    • 18
    • 15
    • 15
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr359

    预测反应

    C, X

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RPS6KA1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T359 of human RPS6KA1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Roux, Ballif, Anjum, Gygi, Blenis: "Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 37, pp. 13489-94, (2004) (PubMed).

    Bohuslav, Chen, Kwon, Mu, Greene: "p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26115-25, (2004) (PubMed).

    Hu, Fang, Dunham, Prada, Stachowiak, Stachowiak: "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling." in: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29325-35, (2004) (PubMed).

    Fernando, Wimalasena: "Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt." in: Molecular biology of the cell, Vol. 15, Issue 7, pp. 3266-84, (2004) (PubMed).

  • 抗原

    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

    别名

    RPS6KA1

    背景

    RPS6KA1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation.

    分子量

    82723

    NCBI登录号

    NP_001006666, NP_002944

    UniProt

    Q15418

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
You are here:
Chat with us!