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Poliovirus Receptor 抗体 (C-Term)

Cited in 3+ publications. This 兔 多克隆 anti-Poliovirus Receptor antibody (Clone RB41981) specifically detects Poliovirus Receptor in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1881709
发货至: 中国
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Quick Overview for Poliovirus Receptor 抗体 (C-Term) (ABIN1881709)

抗原

See all Poliovirus Receptor (PVR) 抗体
Poliovirus Receptor (PVR)

适用

  • 85
  • 17
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宿主

  • 70
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  • 5
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克隆类型

  • 53
  • 41
  • 1
多克隆

标记

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This Poliovirus Receptor antibody is un-conjugated

应用范围

  • 61
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  • 4
  • 2
  • 1
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Western Blotting (WB)

克隆位点

RB41981
  • 抗原表位

    • 9
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    • 2
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    • 1
    • 1
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    AA 314-342, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PVR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the C-terminal region of human PVR.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Nakai, Maniwa, Tanaka, Nishio, Yoshimura, Okita, Ohbayashi, Satoh, Ogita, Takai, Hayashi: "Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma." in: Cancer science, Vol. 101, Issue 5, pp. 1326-30, (2010) (PubMed).

    Carlsten, Norell, Bryceson, Poschke, Schedvins, Ljunggren, Kiessling, Malmberg: "Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 8, pp. 4921-30, (2009) (PubMed).

    Kindberg, Ax, Fiore, Svensson: "Ala67Thr mutation in the poliovirus receptor CD155 is a potential risk factor for vaccine and wild-type paralytic poliomyelitis." in: Journal of medical virology, Vol. 81, Issue 5, pp. 933-6, (2009) (PubMed).

  • 抗原

    Poliovirus Receptor (PVR)

    别名

    PVR

    背景

    The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    45303

    NCBI登录号

    NP_001129240, NP_001129241, NP_001129242, NP_006496

    UniProt

    P15151

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
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