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Poliovirus Receptor 抗体 (C-Term)

This anti-Poliovirus Receptor antibody is a 兔 多克隆 antibody detecting Poliovirus Receptor in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1881709
发货至: 中国

Quick Overview for Poliovirus Receptor 抗体 (C-Term) (ABIN1881709)

抗原

See all Poliovirus Receptor (PVR) 抗体
Poliovirus Receptor (PVR)

适用

  • 64
  • 17
  • 8
  • 1

宿主

  • 55
  • 14
  • 5
  • 1

克隆类型

  • 45
  • 29
  • 1
多克隆

标记

  • 50
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Poliovirus Receptor antibody is un-conjugated

应用范围

  • 49
  • 32
  • 25
  • 21
  • 9
  • 9
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB41981
  • 抗原表位

    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 314-342, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PVR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the C-terminal region of human PVR.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Nakai, Maniwa, Tanaka, Nishio, Yoshimura, Okita, Ohbayashi, Satoh, Ogita, Takai, Hayashi: "Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma." in: Cancer science, Vol. 101, Issue 5, pp. 1326-30, (2010) (PubMed).

    Carlsten, Norell, Bryceson, Poschke, Schedvins, Ljunggren, Kiessling, Malmberg: "Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 8, pp. 4921-30, (2009) (PubMed).

    Kindberg, Ax, Fiore, Svensson: "Ala67Thr mutation in the poliovirus receptor CD155 is a potential risk factor for vaccine and wild-type paralytic poliomyelitis." in: Journal of medical virology, Vol. 81, Issue 5, pp. 933-6, (2009) (PubMed).

  • 抗原

    Poliovirus Receptor (PVR)

    别名

    PVR

    背景

    The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    45303

    NCBI登录号

    NP_001129240, NP_001129241, NP_001129242, NP_006496

    UniProt

    P15151

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
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