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PTBP1 抗体 (N-Term)

Name: PTBP1 抗体 (N-Term)
SKU: ABIN1881702
Availability: OutOfStock

This anti-PTBP1 antibody is a 兔多克隆 antibody detecting PTBP1 in WB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.

PTBP1 Antibody (N-term) (ABIN1881702 and ABIN2838736) western blot analysis in MCF-7 cell line lysates (35 μg/lane). (PTBP1 抗体 (N-Term))

Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using (ABIN1881702 and ABIN2838736). (PTBP1 抗体 (N-Term))

IHC (p)

2 images

(5 references)

产品编号 ABIN1881702

发货至: 中国

Datasheet as PDF

Quick Overview for PTBP1 抗体 (N-Term) (ABIN1881702)

抗原

See all PTBP1 抗体

PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PTBP1 antibody is un-conjugated

应用范围

Western Blotting (WB)

克隆位点

RB40967

Discover our top product PTBP1 Primary Antibody

抗原表位
7

5

4

3

3

2

2

2

1

1

1

1

1
AA 26-55, N-Term

预测反应

B

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This PTBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human PTBP1.

亚型

Ig Fraction
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 45-144) antibody
PTBP1 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 3H8 unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (N-Term) antibody
Verified PTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-100) antibody
PTBP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-290) antibody
PTBP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) antibody
PTBP1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) antibody
PTBP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 8A1 unconjugated Recombinant Antibody

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (N-Term) antibody
PTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-557) antibody
PTBP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 45-145) antibody
PTBP1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3H8 unconjugated

anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) antibody
PTBP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:4000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Osada, Uno, Mineta, Kameoka, Takahashi, Terao: "Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta." in: Molecular ecology, Vol. 19, Issue 14, pp. 2884-95, (2010) (PubMed).

Kanda, Gauss-Müller, Cordes, Tamura, Okitsu, Shuang, Nakamoto, Fujiwara, Imazeki, Yokosuka: "Hepatitis A virus (HAV) proteinase 3C inhibits HAV IRES-dependent translation and cleaves the polypyrimidine tract-binding protein." in: Journal of viral hepatitis, Vol. 17, Issue 9, pp. 618-23, (2010) (PubMed).

Verma, Bhattacharyya, Das: "Polypyrimidine tract-binding protein interacts with coxsackievirus B3 RNA and influences its translation." in: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1245-55, (2010) (PubMed).

Maynard, Hall: "Interactions between PTB RRMs induce slow motions and increase RNA binding affinity." in: Journal of molecular biology, Vol. 397, Issue 1, pp. 260-77, (2010) (PubMed).

Xue, Zhou, Wu, Zhu, Ji, Kwon, Zhang, Yeo, Black, Sun, Fu, Zhang: "Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping." in: Molecular cell, Vol. 36, Issue 6, pp. 996-1006, (2010) (PubMed).
抗原

PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

别名

PTBP1

背景

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.

分子量

57221

NCBI登录号

NP_002810, NP_114367, NP_114368

UniProt

P26599

途径

Regulation of Muscle Cell Differentiation