POLK 抗体 (AA 531-560)
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北京 101111
Quick Overview for POLK 抗体 (AA 531-560) (ABIN1881669)
抗原
See all POLK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 531-560
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This POLK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the Central region of human POLK.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- POLK (Polymerase (DNA Directed) kappa (POLK))
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别名
- POLK
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背景
- External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).
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分子量
- 98809
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NCBI登录号
- NP_057302
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UniProt
- Q9UBT6
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途径
- DNA Damage Repair
抗原
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