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ALIX 抗体 (AA 541-570)

PDCD6IP 适用: 人 WB 宿主: 兔 Polyclonal RB41924 unconjugated
产品编号 ABIN1881644
发货至: 中国
  • 抗原 See all ALIX (PDCD6IP) 抗体
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    抗原表位
    • 15
    • 15
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 541-570
    适用
    • 70
    • 32
    • 31
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 59
    • 11
    • 2
    克隆类型
    • 54
    • 17
    多克隆
    标记
    • 32
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This ALIX antibody is un-conjugated
    应用范围
    • 46
    • 26
    • 26
    • 23
    • 12
    • 11
    • 10
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PDCD6IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-570 amino acids from the Central region of human PDCD6IP.
    克隆位点
    RB41924
    亚型
    Ig Fraction
    Top Product
    Discover our top product PDCD6IP Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Inuzuka, Suzuki, Kawasaki, Shibata, Wakatsuki, Maki: "Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition." in: BMC structural biology, Vol. 10, pp. 25, (2010) (PubMed).

    Shi, Opi, Lugari, Restouin, Coursindel, Parrot, Perez, Madore, Zimmermann, Corbeil, Huang, Arold, Collette, Morelli: "Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X." in: The Biochemical journal, Vol. 431, Issue 1, pp. 93-102, (2010) (PubMed).

    Irie, Inoue, Sakaguchi: "Significance of the YLDL motif in the M protein and Alix/AIP1 for Sendai virus budding in the context of virus infection." in: Virology, Vol. 405, Issue 2, pp. 334-41, (2010) (PubMed).

    Sette, Jadwin, Dussupt, Bello, Bouamr: "The ESCRT-associated protein Alix recruits the ubiquitin ligase Nedd4-1 to facilitate HIV-1 release through the LYPXnL L domain motif." in: Journal of virology, Vol. 84, Issue 16, pp. 8181-92, (2010) (PubMed).

  • 抗原
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    别名
    PDCD6IP (PDCD6IP 产品)
    别名
    DDBDRAFT_0167145 antibody, DDBDRAFT_0185177 antibody, DDB_0167145 antibody, DDB_0185177 antibody, AIP1 antibody, ALIX antibody, DRIP4 antibody, HP95 antibody, AI480591 antibody, AW544830 antibody, Aip1 antibody, Alix antibody, C76364 antibody, Eig2 antibody, mKIAA1375 antibody, CG12876 antibody, DAIP1 antibody, Dmel\\CG12876 antibody, GB11744 antibody, RGD1561176 antibody, zgc:63638 antibody, wu:fb70d03 antibody, wu:fy65h02 antibody, PDCD6IP antibody, aip1 antibody, alix antibody, hp95 antibody, drip4 antibody, ALG-2 interacting protein X antibody, programmed cell death 6 interacting protein antibody, programmed cell death 6-interacting protein antibody, Programmed cell death 6 interacting protein antibody, programmed cell death 6 interacting protein L homeolog antibody, alxA antibody, PDCD6IP antibody, Pdcd6ip antibody, ALiX antibody, LOC412662 antibody, pdcd6ip antibody, Bm1_48390 antibody, pdcd6ip.L antibody
    背景
    This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
    分子量
    96023
    NCBI登录号
    NP_001155901, NP_037506
    UniProt
    Q8WUM4
    途径
    p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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