ALIX 抗体 (AA 541-570)
(4 references)Quick Overview for ALIX 抗体 (AA 541-570) (ABIN1881644)
抗原
See all ALIX (PDCD6IP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 541-570
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PDCD6IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-570 amino acids from the Central region of human PDCD6IP.
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亚型
- Ig Fraction
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anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-239) antibody
PDCD6IP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-180) antibodyPDCD6IP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 174-383) antibodyPDCD6IP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-110) antibodyPDCD6IP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 601-700) antibodyPDCD6IP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) antibodyPDCD6IP 适用: 人 WB, ELISA, FACS 宿主: 兔 Monoclonal 7E9 unconjugated Recombinant Antibody
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) antibodyPDCD6IP 适用: 人, 小鼠, 大鼠, 非洲爪蟾 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition." in: BMC structural biology, Vol. 10, pp. 25, (2010) (PubMed).
: "Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X." in: The Biochemical journal, Vol. 431, Issue 1, pp. 93-102, (2010) (PubMed).
: "Significance of the YLDL motif in the M protein and Alix/AIP1 for Sendai virus budding in the context of virus infection." in: Virology, Vol. 405, Issue 2, pp. 334-41, (2010) (PubMed).
: "The ESCRT-associated protein Alix recruits the ubiquitin ligase Nedd4-1 to facilitate HIV-1 release through the LYPXnL L domain motif." in: Journal of virology, Vol. 84, Issue 16, pp. 8181-92, (2010) (PubMed).
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: "Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition." in: BMC structural biology, Vol. 10, pp. 25, (2010) (PubMed).
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- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
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别名
- PDCD6IP
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背景
- This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
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分子量
- 96023
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NCBI登录号
- NP_001155901, NP_037506
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UniProt
- Q8WUM4
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途径
- p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
抗原
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