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CDKN1B 抗体 (pThr197)

CDKN1B 适用: 小鼠 DB 宿主: 兔 Polyclonal RB42131 unconjugated
产品编号 ABIN1881619
发货至: 中国
  • 抗原 See all CDKN1B 抗体
    CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
    抗原表位
    • 29
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    • 22
    • 19
    • 17
    • 16
    • 11
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    pThr197
    适用
    • 274
    • 125
    • 106
    • 26
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 239
    • 49
    • 2
    • 1
    • 1
    克隆类型
    • 231
    • 61
    多克隆
    标记
    • 142
    • 24
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    • 6
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    • 2
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    • 2
    • 2
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    • 2
    This CDKN1B antibody is un-conjugated
    应用范围
    • 202
    • 134
    • 71
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    • 16
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    Dot Blot (DB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This mouse p27Kip1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T197 of mouse p27Kip1.
    克隆位点
    RB42131
    亚型
    Ig Fraction
    Top Product
    Discover our top product CDKN1B Primary Antibody
  • 应用备注
    DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Singh, Jatzek, Plisch, Srinivasan, Svaren, Suresh: "Regulation of memory CD8 T-cell differentiation by cyclin-dependent kinase inhibitor p27Kip1." in: Molecular and cellular biology, Vol. 30, Issue 21, pp. 5145-59, (2010) (PubMed).

    Antico-Arciuch, Dima, Liao, Refetoff, Di Cristofano: "Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females." in: Oncogene, Vol. 29, Issue 42, pp. 5678-86, (2010) (PubMed).

    Mitsuhashi, Yonemoto, Sone, Kosuge, Kosaki, Takahashi: "In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 37, pp. 16331-5, (2010) (PubMed).

    Zhang, Li, Yuan, Tian, Weidenfeld, Yang, Liu, Chokas, Morrisey: "Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms." in: Genes & development, Vol. 24, Issue 16, pp. 1746-57, (2010) (PubMed).

    Wang, Li, Jiao, Zhang, Shao, Yuan, Yu: "RNA interference reveals a requirement for both p18INK4c and p27Kip1 in B lymphopoiesis." in: Journal of molecular cell biology, Vol. 2, Issue 4, pp. 209-16, (2010) (PubMed).

  • 抗原
    CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
    别名
    p27Kip1 (CDKN1B 产品)
    别名
    CDKN4 antibody, KIP1 antibody, MEN1B antibody, MEN4 antibody, P27KIP1 antibody, cdkn1b antibody, sb:cb611 antibody, wu:fb63g10 antibody, wu:fb64g10 antibody, wu:fe18e03 antibody, CDKN1B antibody, Kip1 antibody, p27 antibody, FAM14D antibody, ISG12 antibody, ISG12A antibody, P27 antibody, Cdki1b antibody, AA408329 antibody, AI843786 antibody, p27Kip1 antibody, cdkn1bl antibody, cyclin dependent kinase inhibitor 1B antibody, cyclin-dependent kinase inhibitor 1Bb antibody, interferon alpha inducible protein 27 antibody, cyclin-dependent kinase inhibitor 1B antibody, cyclin-dependent kinase inhibitor 1Ba antibody, CDKN1B antibody, cdkn1bb antibody, IFI27 antibody, Cdkn1b antibody, cdkn1ba antibody
    背景
    This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].
    分子量
    22193
    NCBI登录号
    NP_034005
    UniProt
    P46414
    途径
    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy
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