NEU1 抗体 (AA 188-214)
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北京 101111
Quick Overview for NEU1 抗体 (AA 188-214) (ABIN1881576)
抗原
See all NEU1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 188-214
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预测反应
- B
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This NEU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-214 amino acids from the Central region of human NEU1.
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亚型
- Ig Fraction
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anti-Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 47-415) antibody
NEU1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 48-315) antibodyNEU1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3D4 unconjugated
anti-Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 334-415) antibodyNEU1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 201-415) antibodyNEU1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sialidase 1 (Lysosomal Sialidase) (NEU1) antibodyNEU1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 156-415) antibodyNEU1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 334-415) antibodyNEU1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sialidase 1 (Lysosomal Sialidase) (NEU1) (Middle Region) antibodyNEU1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 47-415) antibodyNEU1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 2# unconjugated
anti-Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 172-221) antibodyNEU1 适用: 人, 小鼠, 大鼠, Cow, 兔, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients." in: Journal of neurology, Vol. 256, Issue 11, pp. 1911-5, (2009) (PubMed).
: "A longitudinal study of Taiwanese sialidosis type 1: an insight into the concept of cherry-red spot myoclonus syndrome." in: European journal of neurology : the official journal of the European Federation of Neurological Societies, Vol. 16, Issue 8, pp. 912-9, (2009) (PubMed).
: "Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization." in: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28430-41, (2009) (PubMed).
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: "Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients." in: Journal of neurology, Vol. 256, Issue 11, pp. 1911-5, (2009) (PubMed).
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- NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
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别名
- NEU1
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背景
- The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.
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分子量
- 45467
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NCBI登录号
- NP_000425
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UniProt
- Q99519
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途径
- SARS-CoV-2 Protein Interactome
抗原
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