MAVS 抗体 (N-Term)
(1 reference)Quick Overview for MAVS 抗体 (N-Term) (ABIN1881530)
抗原
See all MAVS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Mouse Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs.
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亚型
- Ig Fraction
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anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-65) antibody
MAVS 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 34-96) antibodyMAVS 适用: 人 WB, IHC, ICC, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (C-Term) antibodyMAVS 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-540) antibodyMAVS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 160-450) antibodyMAVS 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal Adri-1 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (N-Term) antibodyMAVS 适用: 人, 小鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 470-519) antibodyMAVS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 146-195) antibodyMAVS 适用: 人, 小鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 477-505) antibodyMAVS 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-30) antibodyMAVS 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Influenza virus activates inflammasomes via its intracellular M2 ion channel." in: Nature immunology, Vol. 11, Issue 5, pp. 404-10, (2010) (PubMed).
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: "Influenza virus activates inflammasomes via its intracellular M2 ion channel." in: Nature immunology, Vol. 11, Issue 5, pp. 404-10, (2010) (PubMed).
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- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
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别名
- Mavs
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背景
- Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
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分子量
- 53399
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NCBI登录号
- NP_001193314, NP_659137
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UniProt
- Q8VCF0
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途径
- Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
抗原
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