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MAP1LC3A 抗体 (pSer12)

This anti-MAP1LC3A antibody is a 兔 多克隆 antibody detecting MAP1LC3A in DB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1881524
发货至: 中国

Quick Overview for MAP1LC3A 抗体 (pSer12) (ABIN1881524)

抗原

See all MAP1LC3A 抗体
MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

适用

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宿主

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克隆类型

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多克隆

标记

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This MAP1LC3A antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB30640
  • 抗原表位

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    pSer12

    预测反应

    Zf, B, M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MAP1LC3A Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S12 of human MAP1LC3A.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Scherz-Shouval, Weidberg, Gonen, Wilder, Elazar, Oren: "p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 43, pp. 18511-6, (2010) (PubMed).

    Cherra, Kulich, Uechi, Balasubramani, Mountzouris, Day, Chu: "Regulation of the autophagy protein LC3 by phosphorylation." in: The Journal of cell biology, Vol. 190, Issue 4, pp. 533-9, (2010) (PubMed).

    Namgoong, Khanal, Cho, Lim, Oh, Kang, Shim, Shim, Yoo, Choi: "The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer." in: The Journal of biological chemistry, Vol. 285, Issue 31, pp. 23829-41, (2010) (PubMed).

    Jiang, Cheng, Liu, Peng, Feng: "Protein kinase C inhibits autophagy and phosphorylates LC3." in: Biochemical and biophysical research communications, Vol. 395, Issue 4, pp. 471-6, (2010) (PubMed).

    Gao, Cao, Bao, Zuo, Xie, Cai, Fu, Zhang, Wu, Zhang, Chen: "Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation." in: Nature cell biology, Vol. 12, Issue 8, pp. 781-90, (2010) (PubMed).

  • 抗原

    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

    别名

    MAP1LC3A

    背景

    MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene.

    NCBI登录号

    NP_115903, NP_852610

    UniProt

    Q9H492, Q9GZQ8

    途径

    Autophagy
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