MAP1LC3A 抗体 (pSer12)
Quick Overview for MAP1LC3A 抗体 (pSer12) (ABIN1881524)
抗原
See all MAP1LC3A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer12
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预测反应
- Zf, B, M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This MAP1LC3A Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S12 of human MAP1LC3A.
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亚型
- Ig Fraction
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应用备注
- DB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 43, pp. 18511-6, (2010) (PubMed).
: "Regulation of the autophagy protein LC3 by phosphorylation." in: The Journal of cell biology, Vol. 190, Issue 4, pp. 533-9, (2010) (PubMed).
: "The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer." in: The Journal of biological chemistry, Vol. 285, Issue 31, pp. 23829-41, (2010) (PubMed).
: "Protein kinase C inhibits autophagy and phosphorylates LC3." in: Biochemical and biophysical research communications, Vol. 395, Issue 4, pp. 471-6, (2010) (PubMed).
: "Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation." in: Nature cell biology, Vol. 12, Issue 8, pp. 781-90, (2010) (PubMed).
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p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 43, pp. 18511-6, (2010) (PubMed).
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- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
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别名
- MAP1LC3A
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背景
- MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene.
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NCBI登录号
- NP_115903, NP_852610
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UniProt
- Q9H492, Q9GZQ8
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途径
- Autophagy
抗原
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