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LIG4 抗体 (N-Term)

This 兔 多克隆 anti-LIG4 antibody (Clone RB40331) specifically detects LIG4 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1881497
发货至: 中国
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Quick Overview for LIG4 抗体 (N-Term) (ABIN1881497)

抗原

See all LIG4 抗体
LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

适用

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宿主

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克隆类型

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多克隆

标记

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This LIG4 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB40331
  • 抗原表位

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    AA 239-267, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This LIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the N-terminal region of human LIG4.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

    别名

    LIG4

    背景

    Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

    分子量

    103971

    NCBI登录号

    NP_001091738, NP_002303, NP_996820

    UniProt

    P49917

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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