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KISS1R 抗体 (AA 235-263)

This anti-KISS1R antibody is a 兔 多克隆 antibody detecting KISS1R in WB. Suitable for 人.
产品编号 ABIN1881480
发货至: 中国

Quick Overview for KISS1R 抗体 (AA 235-263) (ABIN1881480)

抗原

See all KISS1R 抗体
KISS1R (KISS1 Receptor (KISS1R))

适用

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宿主

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克隆类型

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  • 12
多克隆

标记

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This KISS1R antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB40407
  • 抗原表位

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    AA 235-263

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This KISS1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human KISS1R.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    KISS1R (KISS1 Receptor (KISS1R))

    别名

    KISS1R

    背景

    Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

    分子量

    42586

    NCBI登录号

    NP_115940

    UniProt

    Q969F8
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