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ING2 抗体 (AA 112-141)

ING2 适用: 人 WB 宿主: 兔 Polyclonal RB40520 unconjugated
产品编号 ABIN1881460
发货至: 中国
  • 抗原 See all ING2 抗体
    ING2 (Inhibitor of Growth Family, Member 2 (ING2))
    抗原表位
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 112-141
    适用
    • 32
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 26
    • 5
    • 1
    克隆类型
    • 28
    • 4
    多克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ING2 antibody is un-conjugated
    应用范围
    • 24
    • 19
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This ING2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-141 amino acids from the Central region of human ING2.
    克隆位点
    RB40520
    亚型
    Ig Fraction
    Top Product
    Discover our top product ING2 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Ythier, Larrieu, Binet, Binda, Brambilla, Gazzeri, Pedeux: "Sumoylation of ING2 regulates the transcription mediated by Sin3A." in: Oncogene, Vol. 29, Issue 44, pp. 5946-56, (2010) (PubMed).

    Larrieu, Ythier, Binet, Brambilla, Brambilla, Sengupta, Pedeux: "ING2 controls the progression of DNA replication forks to maintain genome stability." in: EMBO reports, Vol. 10, Issue 10, pp. 1168-74, (2009) (PubMed).

    Kumamoto, Fujita, Kurotani, Saito, Unoki, Hagiwara, Shiga, Bowman, Yanaihara, Okamura, Nagashima, Miyamoto, Takenoshita, Yokota, Harris: "ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression." in: International journal of cancer. Journal international du cancer, Vol. 125, Issue 6, pp. 1306-15, (2009) (PubMed).

    Borkosky, Gunduz, Nagatsuka, Beder, Gunduz, Ali, Rodriguez, Cilek, Tominaga, Yamanaka, Shimizu, Nagai: "Frequent deletion of ING2 locus at 4q35.1 associates with advanced tumor stage in head and neck squamous cell carcinoma." in: Journal of cancer research and clinical oncology, Vol. 135, Issue 5, pp. 703-13, (2009) (PubMed).

    Unoki, Kumamoto, Robles, Shen, Zheng, Harris: "A novel ING2 isoform, ING2b, synergizes with ING2a to prevent cell cycle arrest and apoptosis." in: FEBS letters, Vol. 582, Issue 28, pp. 3868-74, (2008) (PubMed).

  • 抗原
    ING2 (Inhibitor of Growth Family, Member 2 (ING2))
    别名
    ING2 (ING2 产品)
    别名
    ING1L antibody, p33ING2 antibody, 2810011M06Rik antibody, Ing1l antibody, Ing2b antibody, P33ING2 antibody, ING2 antibody, INGX antibody, wu:fe11c08 antibody, zgc:92346 antibody, ING1Lp antibody, ing2 antibody, xing2 antibody, inhibitor of growth family member 2 antibody, inhibitor of growth family, member 2 antibody, inhibitor of growth family member 2 S homeolog antibody, inhibitor of growth family member 2 L homeolog antibody, ING2 antibody, Ing2 antibody, ing2.S antibody, ing2 antibody, ing2.L antibody
    背景
    This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.
    分子量
    32808
    NCBI登录号
    NP_001555
    UniProt
    Q9H160
    途径
    Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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